Scavenging ability of dendritic PAMAM bridged hindered phenolic antioxidants towards DPPH˙ and ROO˙ free radicals

Free Radicals, Antioxidants and Disease

Living cells continually generate free radicals or reactive oxygen species (ROS) through the respiratory chain during energetic metabolism. ROS can either be harmful or play important physiological roles in our body. Besides being produced during normal cell metabolism there are numerous exogenous factors, such as irradiation by UV light, X-rays, gamma-rays, and atmospheric pollutants which may...

Free radicals, oxidants, and antioxidants.

Free radicals are species with one or more unpaired electrons. The unpaired electron results in a species that is often highly reactive. Free radicals have a wide range of reactions; two broad classes of reactions are electron transfer and addition reactions resulting in covalent bond formation. Free radicals can be classified as reducing (donating an electron to an acceptor) or oxidizing (acce...

Scavenging Effects of Dexrazoxane on Free Radicals

Dexrazoxane (ICRF-187) has been clinically used to reduce doxorubicin-induced cardiotoxicity for more than 20 years. It has been proposed that dexrazoxane may act through its rings-opened hydrolysis product ADR-925, which can either remove iron from the iron-doxorubicin complex or bind to free iron, thus preventing iron-based oxygen radical formation. However, it is not known whether the antiox...

effect of extraction condition with two ultrasonic methods on phenolic, flavonoids and dpph free radical scavenging of celtis australis extract

plants are rich source of phenolic compounds (phenolic acids, flavonoids and tannins) that are most important natural antioxidants. in the present study two ultrasonic methods including probe and bath were used for the extraction of phenolic and flavonoid compounds from celtis australis. the effects of different extraction time including 30, 60 and 90 min (bath method) and 5, 10 and 20 min (pro...

Interaction between antioxidants and free radicals